Syphilis (Treponema pallidum) 15kDa  +  17kDa  +  47kDa Chimeric Protein

Product code: PVBSP301
For laboratory use

Shipping: Shipped on Dry Ice
Storage Conditions: Store at -20 °C, avoid freeze/thaw cycles
Shelf Life: 12 months
Purity: > 95 % (SDS-PAGE, FPLC)

Host: E.Coli
Form: Liquid (Supplied in 50 mM Tris pH 8.5)
Applications:

• Lateral flow immunoassay: Used for the detection of antibodies against Treponema pallidum in patient samples.
• ELISA: Ideal for detecting syphilis-specific antibodies, allowing for quantitative measurement in serum or plasma.
• Western blots: Confirms the presence of antibodies against Treponema pallidum proteins in patient sera.

Description:
This chimeric recombinant protein includes key antigenic regions from Treponema pallidum, the bacterium responsible for syphilis. The protein encompasses the 15kDa, 17kDa, and 47kDa antigens, providing broad antigenic coverage for diagnostic applications. It is expressed in a bacterial system and purified using advanced chromatographic techniques to ensure high purity and activity.

Background:
Treponema pallidum, the causative agent of syphilis, presents a complex antigenic structure. The detection of antibodies against the 15kDa, 17kDa, and 47kDa antigens is critical for accurate diagnosis of syphilis. The chimeric protein provides comprehensive antigenic coverage, making it a valuable tool for diagnostic assays aimed at identifying syphilis infection, which remains a significant public health concern.

Specificity: Immunoreactive with sera from individuals infected with Treponema pallidum, ensuring accurate detection of syphilis-specific antibodies.

Syphilis Coupling Protein

Product code: PVBSP302
For laboratory use

Shipping: Shipped on Dry Ice
Storage Conditions: Store at -20 °C, avoid freeze/thaw cycles
Shelf Life: 12 months
Purity: > 95 % (SDS-PAGE, FPLC)

Host: E.Coli
Form: Liquid (Supplied in 50 mM Tris pH 8.5)
Applications:

• Lateral flow immunoassay: Detects syphilis antibodies, offering a comprehensive screening tool for syphilis infections.
• ELISA: Suitable for dual-detection assays, enabling simultaneous quantification of syphilis antibodies.
• Western blots: Used for confirmatory testing of syphilis infections, detecting specific antibodies against the coupled antigens.

Description:
The syphilis coupling protein integrates multiple antigenic regions from Treponema pallidum. This fusion protein ensures broad reactivity and is especially useful in diagnostic assays that need to detect antibodies against various syphilis antigens. It is produced in an expression system and purified through advanced chromatographic methods to maintain high purity and functional integrity.

Background:
Syphilis coupling proteins are essential for comprehensive diagnosis of syphilis. The bacterium’s complex structure includes several key antigens that need to be targeted for accurate detection. This coupling protein aids in the reliable diagnosis and monitoring of syphilis infection, which is crucial for patient management and epidemiological studies.

Specificity: Immunoreactive with sera from individuals infected with Treponema pallidum, ensuring comprehensive detection of syphilis-specific antibodies.