HIV1 gp 41+gp120 recombinant protein

Product code: PVBSP101

For  laboratory use

Shipping: shipped on Dry Ice

Storage Conditions: store at -20°C, avoid freeze/thaw cycles

Shelf Life: 12 months

Purity: > 95 % (SDS-PAGE, FPLC)

Molecular weight: 35 kDa

Source: E.coli

Form: liquid (Supplied in 50 mM Tris pH 8.5)

Applications:
Lateral flow immunoassay (for HIV antibody detection) , ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.

Description:
The protein contains the full-length sequence of HIV-1 membrane glycoprotein (gp120) and transmembrane glycoprotein (gp41). The fusion protein was purified by proprietary chromatographic technique.

Background: HIV belongs to the retrovirus family, distinguished by possession of a viral reverse transcriptase that transcribes viral RNA into DNA which is integrated into the host-cell genome. The outer envelope is acquired during virion budding and is studded with spikes formed by the two major viral-envelope glycoproteins (the surface protein gp120 and the transmembrane protein gp41).

Specificity: Immuno reactive with all sera of HIV-1 infected individuals.

 HIV2 gp36 recombinant protein

Product code: PVBSP102  

For laboratory use

Shipping: Shipped on Dry Ice  

Storage Conditions: Store at -20°C, avoid freeze/thaw cycles  

Shelf Life: 12 months  

Purity: > 95 % (SDS-PAGE, FPLC)  

Molecular weight: 12 kDa

Source: E.coli

Form: Liquid (Supplied in 50 mM Tris pH 8.5)  

Applications:  

 Lateral flow immunoassay: Useful for the detection of HIV-2 specific antibodies in patient samples.  

ELISA: Ideal for HIV-2 antibody detection, allowing for quantitative measurement of antibody levels in serum or plasma.  

Western blots: Used in the confirmation of HIV-2 infection by detecting specific antibodies against the gp36 protein in patient sera.  

Description:  

The HIV2 gp36 recombinant protein comprises the full-length sequence of the HIV-2 transmembrane glycoprotein gp36. This protein is pivotal for HIV-2’s ability to fuse with host cells. The recombinant gp36 is produced in a bacterial expression system and purified using proprietary chromatographic techniques to achieve high purity and activity.

Background:  

HIV-2 is one of the two types of human immunodeficiency viruses, the other being HIV-1. HIV-2 is less virulent and less transmissible than HIV-1, but it still poses a significant health risk. The gp36 protein is a component of the viral envelope and plays a crucial role in the virus’s ability to enter host cells. Studying and detecting this protein is essential for understanding HIV-2’s pathogenesis and for developing diagnostic assays.

Specificity: Immunoreactive with sera from individuals infected with HIV-2, ensuring accurate detection of HIV-2 specific antibodies.

 HIV1+HIV2 coupling protein

Product code: PVBSP103  

For laboratory use

Shipping: Shipped on Dry Ice  

Storage Conditions: Store at -20°C, avoid freeze/thaw cycles  

Shelf Life: 12 months  

Purity: > 95 % (SDS-PAGE, FPLC)  

Molecular weight: 54 kDa

Source: E.coli

Form: Liquid (Supplied in 50 mM Tris pH 8.5)  

Applications:  

 Lateral flow immunoassay: Detects both HIV-1 and HIV-2 antibodies, providing a comprehensive screening tool for HIV infections.  

ELISA: Suitable for dual-detection assays, enabling simultaneous quantification of HIV-1 and HIV-2 antibodies.  

 Western blots: Used for confirmatory testing of HIV-1 and HIV-2 infections, detecting specific antibodies against the coupled antigens.

Description:  

The HIV1+HIV2 coupling protein integrates antigenic regions from both HIV-1 and HIV-2. This fusion protein ensures broad reactivity and is especially useful in diagnostic assays that need to distinguish or detect both types of HIV. It is produced in an expression system and purified through advanced chromatographic methods to maintain high purity and functional integrity.

Background:  

The combination of HIV-1 and HIV-2 antigens provides a robust tool for the comprehensive diagnosis of HIV. While HIV-1 is more prevalent worldwide, HIV-2 is found in specific regions, such as West Africa. This coupling protein aids in the accurate diagnosis and monitoring of both HIV types, which is crucial for patient management and epidemiological studies.

Specificity: Immunoreactive with sera from individuals infected with either HIV-1 or HIV-2, ensuring comprehensive detection.

HIV p24 recombinant protein

Product code: PVBSP104  

For laboratory use

Shipping: Shipped on Dry Ice  

Storage Conditions: Store at -20°C, avoid freeze/thaw cycles  

Shelf Life: 12 months  

Purity: > 95 % (SDS-PAGE, FPLC)  

Molecular weight: 24 kDa

Form: Liquid (Supplied in 50 mM Tris pH 8.5)  

Applications:  

Lateral flow immunoassay: As a positive control of p24 antigen.

ELISA: Used for the early detection of HIV infection by quantifying p24 antigen levels in blood.  

 Western blots: Confirms the presence of HIV infection by detecting p24 antigen in patient samples.  

Research: Ideal for studying HIV pathogenesis, viral assembly, and immune responses.

Description:  

Recombinant HIV p24 protein represents the viral core protein, which is one of the first detectable antigens following HIV infection. This protein is crucial for virus assembly and maturation. The recombinant p24 protein is produced in a bacterial expression system and purified using proprietary chromatographic techniques to ensure high purity and activity.

Background:  

The p24 protein is a core component of the HIV capsid, playing a significant role in the early stages of HIV infection. It is one of the earliest markers detectable in the blood following HIV infection, making it essential for early diagnosis. Detection of p24 is a critical step in HIV testing algorithms, especially during the window period before antibodies become detectable.

Specificity: Immunoreactive with sera from HIV-infected individuals, ensuring accurate detection of p24 antigen.

Anti-HIV p24 Monoclonal Antibody (Primary Antibody)

Product code: PVBSP105  

For laboratory use

Shipping: Shipped on Dry Ice  

Storage Conditions: Store at -20°C, avoid freeze/thaw cycles  

Shelf Life: 12 months  

Purity: > 98 % (SDS-PAGE, FPLC)  

Molecular weight: 150 kDa

Source: Mouse

Form: Liquid (Supplied in PBS, pH 7.4)  

Applications:  

Lateral flow immunoassay: For p24 antigen detection in a double antibody sandwich method.

ELISA: Detects HIV p24 antigen, facilitating early diagnosis and monitoring of HIV infection.  

Western blots: Used to confirm the presence of p24 antigen in HIV-infected samples.  

Immunohistochemistry: Allows for the visualization of p24 antigen in tissue samples, aiding in research and diagnostic studies.

Description:  

This monoclonal antibody is highly specific to the HIV p24 antigen, a key component of the viral core. The antibody is produced using hybridoma technology and purified using proprietary chromatographic techniques to ensure high specificity and binding affinity.

Background:  

Monoclonal antibodies against HIV p24 are crucial for diagnostic and research purposes. They enable the detection of the p24 antigen, which is a reliable marker for early HIV infection. These antibodies are indispensable in developing sensitive and specific diagnostic assays.

Specificity: Highly specific to HIV p24 antigen, ensuring precise detection in various applications.

 Anti-p24 Monoclonal Antibody (Secondary antibody)

Product code: PVBSP106  

For laboratory use

Shipping: Shipped on Dry Ice  

Storage Conditions: Store at -20°C, avoid freeze/thaw cycles  

Shelf Life: 12 months  

Purity: > 98 % (SDS-PAGE, FPLC)  

Source: Mouse

Molecular weight: 150 kDa

Form: Liquid (Supplied in PBS, pH 7.4)  

Applications:  

Lateral flow immunoassay: As a secondary antibody, it can be conjugated with colloidal gold or any other fluorophore of choice.

ELISA: Used for detecting p24 antigen, aiding in the diagnosis and monitoring of early HIV infection.  

 Western blots: Confirms the presence of p24 antigen in HIV-infected samples.  

Immunohistochemistry: Visualizes p24 antigen in tissue samples, providing valuable insights in research studies.

Description:  

This monoclonal antibody targets the p24antigen, a crucial component of the viral envelope. The antibody is developed through hybridoma technology and purified using proprietary chromatographic techniques, ensuring high specificity and binding affinity.

Background:  

Monoclonal antibodies against HIV p24 are crucial for diagnostic and research purposes. They enable the detection of the p24 antigen, which is a reliable marker for early HIV infection. These antibodies are indispensable in developing sensitive and specific diagnostic assays.

Specificity: Highly specific to HIV p24 antigen, ensuring precise detection in various applications.